Generic Omnicef (Cefdinir) 300 mg
Paget’s disease, osteoporosis in postmenopausal women (prevention of bone fractures, incl hip and spine), osteoporosis in men, hypercalcemia of malignant tumors.
Hypersensitivity, pregnancy, lactation, infancy (safety and efficacy are not currently defined). Diseases of the digestive tract in the acute phase (dysphagia, esophagitis, gastritis, duodenitis, peptic ulcer and 12 duodenal ulcer), esophageal stricture, achalasia of the esophagus, chronic renal failure (creatinine clearance less than at 35 ml / min increases the risk of accumulation of the drug), hypocalcemia, vitamin D deficiency .
Part of the digestive system: stomach pain, dysphagia, heartburn, esophagitis, peptic ulcer or erosion of the esophagus, gastralgia, dyspepsia, flatulence, constipation or diarrhea, and nausea. CNS: headache, irritability. For the skin: skin rash, redness of the skin. Other: myalgia, asymptomatic hypocalcemia and hypophosphatemia. Overdosage treatment: milk or Ca2 +-containing antacids to bind the drug (because of the risk of esophageal irritation should not induce vomiting.)
Dosage and administration:
Inside, a once a day, without chewing, for 2 hours (at least 30 minutes) before the first meal, water or other drugs. Drink only plain water. Osteoporosis in postmenopausal women – 10 mg / day for prophylaxis – 5 mg / day. In Paget’s disease – 40 mg / day for 6 months.
Just drink plain water because other drinks (including mineral water, coffee, tea, orange juice) reduce the absorption. To reduce the irritating effects on the esophagus should be taken immediately after the morning rise, with a full glass of water after taking should not lie down for 30 minutes (dangerous to apply in the case of the patient’s inability to stand or sit upright for 30 minutes). Reception at bedtime or in a horizontal position increases the risk of esophagitis. In the presence of hypocalcemia is necessary to correct it before starting treatment. Therapy should be combined with a diet enriched with salts Ca2+.