Right Ventricular Hypertrophy Detected by Echocardiography in Patients with Newly Diagnosed Obstructive Sleep Apnea (1)

Right Ventricular Hypertrophy Detected by Echocardiography in Patients with Newly Diagnosed Obstructive Sleep Apnea (1)Right ventricular hypertrophy in OSA patients may occur as a consequence of pulmonary hypertension secondary to transient hypoxemia. Systemic hypertension with LVH has been described in OSA patients. There have been studies of right ventricular failure in OSA patients, but the incidence and pathogenesis of RVH and OSA have not been reported. In addition, no data are available on the prevalence of RVH in patients with newly diagnosed OSA or on the use of echocardiography to detect ventricular hypertrophy in these patients.
Materials and Methods
We conducted a prospective study of 50 consecutive patients referred to our sleep laboratory for evaluation of possible OSA. All patients gave informed consent, and the study was approved by the Institutional Review Board at Memorial Medical Center. Using standard polysomnographic techniques, we performed an overnight sleep study on each patient. The techniques included electrooculograms (right and left outer canthi); electroencephalograms (C4-A1, 01-A2); mental and submental electromyelograms; electrocardiograms; measurement, by impedance, of chest and abdominal wall movement (Rochester cardiopneumography box); measurement, by thermistor, of nasal and oral air flow; and continuous digital pulse oximetry (Nellcor N-100). The data were recorded on a 12- or 21-channel Nihon Kohden polygraph recorder at 10 mm/s.