Right Ventricular Hypertrophy Detected by Echocardiography in Patients with Newly Diagnosed Obstructive Sleep Apnea (10)

We feel that the incidence of RVH is great even if our criterion of RVT ^6mm is too liberal, even though ^5mm is the accepted standard measurement. We feel that early recognition of RVH using echocardiography as an adjunct to polysomnography in patients that fit a particular pattern may help prevent subsequent RVH and right ventricular failure.
A limitation of this study is that no other measurement of RVH was attempted. Electrocardiogram abnormalities are seen late in the course of RVH. Cine-MRI is in a very early stage of development. We also did not use Doppler measurements of tricuspid regurgitation velocity or first pass right ventriculography for RVT corroboration. These techniques may have been useful for detection of early right ventricular abnormalities.
We attempted multivariate testing in order to show interaction of variables and possibly look at the pathogenesis of RVH, but no significance was found. Because of this, we have started to enlarge our sample size in order to try to determine those variables that are significant in multivariate testing and significant in the pathogenesis of RVH. We will evaluate what degree of RVT is reversible with appropriate therapy for OSA and what degree of RVT correlates with the development of cor pulmonale in OSA.