The Role of Coronary Arteriography in Demonstration of Mural Thrombosis after Angioplasty (9)

The Role of Coronary Arteriography in Demonstration of Mural Thrombosis after Angioplasty (9)Therefore, univariate analysis showed that thrombus size, presence of slowed flow, and fibrin composition were associated with a positive angiogram. Fitting of a logistic regression model incorporating all three variables in 26 specimens confirmed the abovementioned influence of thrombus size on the outcome of arteriography. Neither fibrin composition nor slowed flow added independent information on the outcome of arteriography, suggesting that their contribution is already shared by the variable thrombus size.
Discussion
Our study provided an objective experimental demonstration of the low accuracy of arteriography for detection of mural thrombosis after angioplasty. Since the specificity of angiographic findings approached 100 percent, the low accuracy was due almost entirely to low sensitivity.
Mechanisms Influencing Thrombus Demonstration
Several factors can have influenced thrombus demonstration at arteriography. First, in 67 percent of AT— dogs with mural thrombi, the thrombus was actually small and conceivably less likely to appear on the arteriogram. The present study shows that encroachment of about one fourth of the arterial lumen is a minimal necessary condition for thrombosis to appear on the arteriogram in this model. This value, however, needs to be validated prospectively.